Article
Application of SNPs with low minor allele frequencies in missing person identification (MPI) through kinship analysis of DNA mixtures.
Electrophoresis - 1 Oct 2023
Zhang Nan, Shi Shanshan, Lin Shaobin, Bai Zhaochen, Ling Xiaohua, Gao Jun, Yan Ruiling, Ou Xueling
Abstract excerpt
The need to identify a missing person (MP) through kinship analysis of DNA samples found at a crime scene has become increasingly prevalent. DNA samples from MPs can be severely degraded, contain little DNA and mixed with other contributors, which often makes it difficult to apply conventional methods in practice. This study developed a massively parallel sequencing-based panel that contains 1661...
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