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Article

Neuroimaging changes in the pregeniculate visual pathway and chiasmal enlargement in Leber hereditary optic neuropathy.

The British journal of ophthalmology - 22 Aug 2024

Xu Xintong, Zhou Huanfen, Sun Mingming, Li Yuyu, Chen Biyue, Chen Xiyun, Xu Quangang, Yu-Wai-Man Patrick, Wei Shihui

Abstract excerpt

PURPOSE: To describe the pattern of MRI changes in the pregeniculate visual pathway in Leber hereditary optic neuropathy (LHON). METHOD: This retrospective observational study enrolled 60 patients with LHON between January 2015 and December 2021. The abnormal MRI features seen in the pregeniculate visual pathway were investigated, and then correlated with the causative mitochondrial DNA (mtDNA) mutation, the...

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Identifiers

PMID: 38237954
DOI: 10.1136/bjo-2023-324628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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