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Article

Optic nerve lesion length is a biomarker of visual disability in the pre-chronic phase of Leber's hereditary optic neuropathy.

Clinical neurology and neurosurgery - 1 Jan 2023

Zhao Juan, Sun Houliang, Zhu Hongyu, Chang Qinglin, Wang Jiawei

Abstract excerpt

OBJECTIVE: The current research aims to investigate relationships between the optic nerve (ON) lesion length with visual function in the pre-chronic phase ( illness duration < 12 months) of LHON. METHODS: Orbital MRI was retrospectively analyzed for 45 patients with LHON in the pre-chronic phase. ON lesion length was measured by 2 trained independent readers and it was recorded as multiplication of the number of...

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PMID: 36459841
DOI: 10.1016/j.clineuro.2022.107542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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