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Article

Leber Hereditary Optic Neuropathy in Southwestern Ontario: A Growing List of Mutations.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Sept 2023

McDonald Heather M, Sadikovic Bekim, Sheldon Claire A, Bursztyn Lulu L C D

Abstract excerpt

BACKGROUND: Leber hereditary optic neuropathy (LHON) is a rare but bilaterally blinding disease. Three characteristic disease-causing point mutations, and other less common mutations, are most often found on the mitochondrially encoded genes of NADH-ubiquinone oxidoreductase core subunits (MT-ND). The purpose of this study is to provide an overview of LHON mutations in Southwestern Ontario and to describe the...

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Identifiers

PMID: 35892476
DOI: 10.1017/cjn.2022.279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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