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Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus

16 Jan 2024

Abstract excerpt

Covalently closed circular DNA plays a key role for the persistence of hepatitis B virus (HBV) since it serves as the template for viral transcription. Identification of transcription factors that regulate HBV transcription not only provides insights into molecular mechanisms of viral life cycle regulation but may also provide potential antiviral targets. In this work, we identified host MSX1 as a novel...

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PMID: 38226815
DOI: 10.1128/jvi.01345-23

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