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Senolytic treatment alleviates doxorubicin‐induced chemobrain

15 Jan 2024

Abstract excerpt

Doxorubicin (Dox), a widely used treatment for cancer, can result in chemotherapy-induced cognitive impairments (chemobrain). Chemobrain is associated with inflammation and oxidative stress similar to aging. As such, Dox treatment has also been used as a model of aging. However, it is unclear if Dox induces brain changes similar to that observed during aging since Dox does not readily enter the brain. Rather, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38225896
DOI: 10.1111/acel.14037

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