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Article

A cryptozoospermic infertile male with Y chromosome AZFc microdeletion and low FSH levels due to a simultaneous polymorphism in the FSHB gene: a case report.

Human reproduction (Oxford, England) - 1 Mar 2024

Graziani Andrea, Merico Maurizio, Grande Giuseppe, Di Mambro Antonella, Vinanzi Cinzia, Rocca Maria Santa, Selice Riccardo, Ferlin Alberto

Abstract excerpt

Genetic causes account for 10-15% of male factor infertility, making the genetic investigation an essential and useful tool, mainly in azoospermic and severely oligozoospermic men. In these patients, the most frequent findings are chromosomal abnormalities and Y chromosome long arm microdeletions, which cause a primary severe spermatogenic impairment with classically increased levels of FSH. On the other hand,...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Y

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follicle Stimulating Hormone, beta Subunit

Share to Infertility, Male

Share to Oligospermia

Share to Polymorphism, Single Nucleotide

Share to Sex Chromosome Aberrations

Source

Identifiers

PMID: 38224259
DOI: 10.1093/humrep/dead277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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