Article
Distinct Inflammatory Phenotypes Are Associated With Subclinical and Clinical Cardiovascular Disease in People With Human Immunodeficiency Virus.
The Journal of infectious diseases - 23 Sept 2024
McGettrick Padraig, Tinago Willard, O'Brien Julie, Miles Sarah, Lawler Leo, Garcia-Leon Alejandro, Mahon Niall, Lambert John, Sheehan Gerard, Landay Alan, Sabin Caroline A, Cotter Aoife G, Mallon Patrick W G
Abstract excerpt
Despite inflammation being implicated in cardiovascular disease (CVD) in people with human immunodeficiency virus (PWH), considerable heterogeneity within populations of PWH exists. Stratifying CVD risk based on inflammatory phenotype could play an important role. Using principal component analyses and unsupervised hierarchical clustering, we examined 38 biomarkers to identify inflammatory phenotypes in 2...
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