Article
Bullous Pemphigoid: Trigger and Predisposing Factors.
Biomolecules - 10 Oct 2020
Moro Francesco, Fania Luca, Sinagra Jo Linda Maria, Salemme Adele, Di Zenzo Giovanni
Abstract excerpt
Bullous pemphigoid (BP) is the most frequent autoimmune subepidermal blistering disease provoked by autoantibodies directed against two hemidesmosomal proteins: BP180 and BP230. Its pathogenesis depends on the interaction between predisposing factors, such as human leukocyte antigen (HLA) genes, comorbidities, aging, and trigger factors. Several trigger factors, such as drugs, thermal or electrical burns,...
Topics
- Causality
- Comorbidity
- Disease Susceptibility
- Drug-Related Side Effects and Adverse Reactions
- Gene-Environment Interaction
- Genetic Predisposition to Disease
- HLA Antigens
- Humans
- Infections
- Pemphigoid, Bullous
- Prognosis