Article
Actionable mutational profiling in solid tumors using hybrid-capture-based next-generation sequencing in a real-world setting in Spain.
Cancer medicine - 1 Feb 2024
Zazo Sandra, Pérez-Buira Sandra, Carvajal Nerea, Plaza-Sánchez Jenifer, Manso Rebeca, Pérez-González Nuria, Dominguez Carolina, Prieto-Potin Iván, Rubio Jaime, Dómine Manuel, Lozano Virginia, Mohedano Patricia, Carcedo David, Carias Rafael, Rojo Federico
Abstract excerpt
OBJECTIVE: This study aimed to describe the performance of a next-generation sequencing (NGS) panel for the detection of precise genomic alterations in cancer in Spanish clinical practice. The impact of tumor characteristics was evaluated on informative NGS and actionable mutation rates. MATERIALS AND METHODS: A cross-sectional study was conducted at the Fundación Jiménez Díaz University Hospital (May 2021-March...
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