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Single-cell profiling reveals transcriptome dynamics during bovine oocyte growth

5 Apr 2024

Abstract excerpt

BACKGROUND: Mammalian follicle development is characterized by extensive changes in morphology, endocrine responsiveness, and function, providing the optimum environment for oocyte growth, development, and resumption of meiosis. In cattle, the first signs of transcription activation in the oocyte are observed in the secondary follicle, later than during mouse and human oogenesis. While many studies have generated...

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PMID: 38580918
DOI: 10.1186/s12864-024-10234-0

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