Article
TCF21 rs2327429 and TCF21 rs12190287 are associated with colorectal cancer in a Chinese population.
Biomarkers in medicine - 1 Sept 2023
Wang Jian-Guo, Jin Xia-Fang, Huang Yi-Min, Xu Zheng-Fen, Huang Shou-Ju, Zhu Yingjie, Ai Ling, Hang Tian
Abstract excerpt
Aims: TCF21 is considered a tumor suppressor gene. This work was designed to explore the associations between TCF21 polymorphisms and colorectal cancer (CRC) susceptibility. Methods: A case-control study was designed with 421 patients with CRC and 469 non-CRC controls. Six tagging single-nucleotide polymorphisms (rs2327429 T>C, rs2327430 T>C, rs2327433 A>G, rs12190287 C>G, rs7766238 G>A and T>A) were...
