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Article

Pay Attention to the Osteochondromas in Fibrodysplasia Ossificans Progressiva.

Orthopaedic surgery - 1 Mar 2024

Li Longqing, Lu Minxun, He Xuanhong, Zou Chang, Zheng Chuanxi, Wang Yitian, Tang Fan, Luo Yi, Zhou Yong, Min Li, Tu Chongqi

Abstract excerpt

BACKGROUND: Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease characterized by malformation of the bilateral great toes and progressive heterotopic ossification. The clinical features of FOP occur due to dysfunction of the bone morphogenetic protein (BMP) signaling pathway induced by the mutant activin A type I receptor/activin-like kinase-2 (ACVR1/ALK2) which contributes to the clinical...

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Identifiers

PMID: 38185793
DOI: 10.1111/os.13956
PMCID: PMC10925518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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