Article
Epigenetic Control of Adamantinomatous Craniopharyngiomas.
The Journal of clinical endocrinology and metabolism - 16 Sept 2024
Marrero-Gutiérrez Junier, Bueno Ana Carolina, Martins Clarissa Silva, Coeli-Lacchini Fernanda Borchers, Silva-Júnior Rui M Patrício, Marques Gonçalves Gabriel Henrique, Ozaki Jorge Guilherme Okanobo, de Almeida E Silva Danillo C, Wildemberg Luiz Eduardo, da Silva Antunes Ximene Lima, Dos Santos Antônio Carlos, Machado Helio Rubens, Santos Marcelo Volpon, Moreira Ayrton Custodio, Gadelha Monica R, Vêncio Ricardo Zorzetto Nicoliello, Antonini Sonir Roberto R, de Castro Margaret
Abstract excerpt
INTRODUCTION: Studies addressing the methylation pattern in adamantinomatous craniopharyngioma (ACP) are lacking. OBJECTIVE: To identify methylation signatures in ACPs regarding clinical presentation and outcome. METHODS: Clinical and pathology data were collected from 35 patients with ACP (54% male; 18.1 years [2-68]). CTNNB1 mutations and methylation profile (MethylationEPIC/Array-Illumina) were analyzed in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
