Article
Additive and Interactive Associations of Environmental and Sociodemographic Factors with the Genotypes of Three Glutathione S-Transferase Genes in Relation to the Blood Arsenic Concentrations of Children in Jamaica.
International journal of environmental research and public health - 1 Jan 2022
Rahbar Mohammad H, Samms-Vaughan Maureen, Zhao Yuansong, Saroukhani Sepideh, Zaman Sheikh F, Bressler Jan, Hessabi Manouchehr, Grove Megan L, Shakspeare-Pellington Sydonnie, Loveland Katherine A
Abstract excerpt
Arsenic (As) is a metalloid that has been classified as a xenobiotic with toxic effects on human beings, especially on children. Since the soil in Jamaica contains As, dietary intake is considered the main source of As exposure in Jamaicans. In addition, glutathione S-transferase (GST) genes, including GSTT1, GSTP1, and GSTM1, play an important role in the metabolism of xenobiotics including As in humans. Using...
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