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Article

Role of metabolic genes in blood arsenic concentrations of Jamaican children with and without autism spectrum disorder.

International journal of environmental research and public health - 6 Aug 2014

Rahbar Mohammad H, Samms-Vaughan Maureen, Ma Jianzhong, Bressler Jan, Loveland Katherine A, Ardjomand-Hessabi Manouchehr, Dickerson Aisha S, Grove Megan L, Shakespeare-Pellington Sydonnie, Beecher Compton, McLaughlin Wayne, Boerwinkle Eric

Abstract excerpt

Arsenic is a toxic metalloid with known adverse effects on human health. Glutathione-S-transferase (GST) genes, including GSTT1, GSTP1, and GSTM1, play a major role in detoxification and metabolism of xenobiotics. We investigated the association between GST genotypes and whole blood arsenic concentrations (BASC) in Jamaican children with and without autism spectrum disorder (ASD). We used data from 100 ASD cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25101770
DOI: 10.3390/ijerph110807874
PMCID: PMC4143838

Genes

GSTP1
GSTM1
GSTT1

Provenance

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