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Article

[EGFR Exon 20 Insertion Mutation: Research Status and New Treatment Strategies].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Aug 2024

Tian Mengwei, Wang Na, Dou Zhanjun, Song Xia, Zhang Xia

Abstract excerpt

In non-small cell lung cancer (NSCLC), as an improtant oncogenic driver gene, epidermal growth factor receptor exon 20 insertion (EGFR ex20ins) has a unique protein structure and is primarily drug-resistant to traditional EGFR-tyrosine kinase inhibitors (EGFR-TKIs). In recent years, exploration of targeted therapy for EGFR ex20ins has never stopped. Firstly Mobocertinib and Amivantamab obtained approval from U.S....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39318251
DOI: 10.3779/j.issn.1009-3419.2024.106.19
PMCID: PMC11425684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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