[Hypothesis of Genetic Diversity Selection in the Occurrence and Development of 
Lung Cancer: Molecular Evolution and Clinical Significance].

Abstract excerpt

So far, the monoclonal hypothesis of tumor occurrence and development cannot be justified. The genetic diversity selection hypothesis for the occurrence and development of lung cancer links Mendelian genetics with Darwin's theory of evolution, suggesting that the genetic diversity of tumor cell populations with polyclonal origins-monoclonal selection-subclonal expansion is the result of selection pressure. Normal...

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