Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using the Bayesian variational spike and slab model in a genome-wide association study for finding associated loci with bipolar disorder.

Annals of human genetics - 1 May 2024

Kazemi Naeini Maryam, Akbarzadeh Mahdi, Kazemi Iraj, Speed Doug, Hosseini Sayed Mohsen

Abstract excerpt

OBJECTIVE: The genome-wide association studies (GWAS) analysis, the most successful technique for discovering disease-related genetic variation, has some statistical concerns, including multiple testing, the correlation among variants (single-nucleotide polymorphisms) based on linkage disequilibrium and omitting the important variants when fitting the model with just one variant. To eliminate these problems in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CDH23 gene

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 38161273
DOI: 10.1111/ahg.12538

Genes

APP
ARL8A
CDH23
ELF3
GABPA
GPR37L1
JAM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using the Bayesian variational spike and slab model in a genome-wide association study for finding associated loci with bipolar disorder.PMID 38161273Read ↗

Genetic associations between bipolar disorder and brain structural phenotypes.Semantic proximity Read ↗

Bayesian modelling in genetic association studiesSemantic proximity Read ↗

SNP Data Science for Classification of Bipolar Disorder I and Bipolar Disorder II.Semantic proximity Read ↗

Statistical methods for testing X chromosome variant associations: application to sex-specific characteristics of bipolar disorder.Semantic proximity Read ↗

SNP fine mapping of chromosome 8q24 in bipolar disorder.Semantic proximity Read ↗

A Bayesian clustering approach for detecting gene-gene interactions in high-dimensional genotype data.Semantic proximity Read ↗

SMetABF: A rapid algorithm for Bayesian GWAS meta-analysis with a large number of studies included.Semantic proximity Read ↗

Family-based SNP association study on 8q24 in bipolar disorder.Semantic proximity Read ↗

Classification of patients with lithium-treated bipolar disorder based on gene expression: Dirichlet Bayesian network modelSemantic proximity Read ↗

Genome-Wide Association Analysis and Genomic Prediction of Thyroglobulin Plasma Levels.Semantic proximity Read ↗

Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder.Semantic proximity Read ↗

Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.