Article
In vivo challenge studies on vaccinated chickens indicate a virus genotype mismatched vaccine still offers significant protection against NDV.
Vaccine - 25 Jan 2024
Mahmood Sahar, Skinner Paul, Warren Caroline J, Mayers Jo, James Joe, Núñez Alejandro, Lean Fabian Z X, Brookes Sharon M, Brown Ian H, Banyard Ashley C, Ross Craig S
Abstract excerpt
Although commercial vaccines against Newcastle Disease have been available for decades, outbreaks still occur in the face of vaccination Further vaccination may accelerate viral evolution resulting in a further reduction in vaccine efficacy. A key question is whether genotype-matched vaccines can confer better protection against contemporary type 1 Avian Paramyxoviruses. To assess this, an in vivo...
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