Antigenic differences among Newcastle disease virus strains of different genotypes used in vaccine formulation affect viral shedding after a virulent challenge.

Abstract excerpt

Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype. It is widely recognized that an efficacious Newcastle disease (ND) vaccine made with any NDV does induce protection against morbidity and mortality from a virulent NDV challenge. However, those ND vaccines do not protect vaccinates from...

Topics

• Animals
• Antibodies, Viral
• Antigens, Viral
• Chickens
• Enzyme-Linked Immunosorbent Assay
• Genome, Viral
• Genotype
• Hemagglutination Inhibition Tests
• Molecular Sequence Data
• Mouth
• Newcastle Disease