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Evaluation of genotype matched recombinant DNA vaccine for protection against genotype VII velogenic Newcastle disease virus in Pakistan.

Scientific reports - 30 Dec 2025

Razzaq Saddaf, Riaz Aayesha, Siddique Naila, Saif-Ur-Rehman, Shah Muhammad Ali, Naeem Khalid, Saleem Gulbeena

Abstract excerpt

Newcastle disease virus (NDV) remains a major threat to the poultry industry worldwide. Recombinant DNA vaccine against NDV offers a promising solution to current Newcastle disease (ND) challenges. Present study describes the development of a DNA vaccine (rDNA-NDV-F) using the fusion (F) gene from NDV genotype VII strain isolated from Rawalpindi, Pakistan. While conventional NDV vaccines reduce mortality in...

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Identifiers

PMID: 41469801
DOI: 10.1038/s41598-025-34387-4
PMCID: PMC12864952

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Evaluation of genotype matched recombinant DNA vaccine for protection against genotype VII velogenic Newcastle disease virus in Pakistan.PMID 41469801Read ↗

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