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Can genotype mismatch really affect the level of protection conferred by Newcastle disease vaccines against heterologous virulent strains?

Vaccine - 22 Jun 2018

Liu Haijin, de Almeida Renata Servan, Gil Patricia, Majó Natàlia, Nofrarías Miquel, Briand François-Xavier, Jestin Véronique, Albina Emmanuel

Abstract excerpt

Newcastle disease (ND), caused by virulent class II avian paramyxovirus 1 (Newcastle disease virus, NDV), occurs sporadically in poultry despite their having been immunized with commercial vaccines. These vaccines were all derived from NDV strains isolated around 70 years ago. Since then, class II NDV strains have evolved into 18 genotypes. Whether the vaccination failure results from genotype mismatches between...

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Identifiers

PMID: 29843999
DOI: 10.1016/j.vaccine.2018.05.074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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