Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of a human iPSC line (CHCMUi002-A) from peripheral blood mononuclear cells from a chronic granulomatous disease patient.

Stem cell research - 1 Feb 2024

Zeng Anle, Ni Ke, Fang Shuyu, Yu Lang, Gao Yelei, Zhou Lina, Zhao Xiaodong

Abstract excerpt

Chronic granulomatous disease (CGD) is a rare X-linked recessive primary immunodeficiency disease (PID). Herein, a human induced pluripotent stem cell (iPSC) line was generated from the peripheral blood mononuclear cells (PBMCs) of a CGD patient with a mutation (c.785_786delTT) in the CYBB gene. These iPSCs showed the expression of pluripotency markers, the ability to differentiate into three germ layers. They...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Granulomatous Disease, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Induced Pluripotent Stem Cells

Share to Leukocytes, Mononuclear

Share to Mutation

Source

Identifiers

PMID: 38134578
DOI: 10.1016/j.scr.2023.103269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of a human iPSC line (CHCMUi002-A) from peripheral blood mononuclear cells from a chronic granulomatous disease patient.PMID 38134578Read ↗

A Mouse Model of X-Linked Chronic Granulomatous Disease for the Development of CRISPR/Cas9 Gene Therapy.Semantic proximity Read ↗

Gene symbol: CYBB. Disease: X-linked chronic granulomatous disease.Semantic proximity Read ↗

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells.Semantic proximity Read ↗

Targeted Repair of CYBB in X-CGD iPSCs Requires Retention of Intronic Sequences for Expression and Functional Correction.Semantic proximity Read ↗

Identification of a novel mutation in CYBB gene in a Chinese neonate with X-linked chronic granulomatous disease: A case report.Semantic proximity Read ↗

Generation of iPSC line (GLNNFi001-A) from peripheral blood mononuclear cells of a patient with macular corneal dystrophy.Semantic proximity Read ↗

Generation of a human induced pluripotent stem cell line (CMCi002-A) from a patient with Gitelman's syndrome.Semantic proximity Read ↗

Chronic granulomatous disease: Clinical, molecular, and therapeutic aspects.Semantic proximity Read ↗

Functional Restoration of gp91phox-Oxidase Activity by BAC Transgenesis and Gene Targeting in X-linked Chronic Granulomatous Disease iPSCs.Semantic proximity Read ↗

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease.Semantic proximity Read ↗

Gene Therapy for Chronic Granulomatous Disease: Current Status and Future PerspectivesSemantic proximity Read ↗

Case report: a case of CYBB gene variant in X-linked chronic granulomatous disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.