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Article

Discovery and verification of extracellular microRNA biomarkers for diagnostic and prognostic assessment of preeclampsia at triage

20 Dec 2023

Abstract excerpt

We report on the identification of extracellular miRNA (ex-miRNA) biomarkers for early diagnosis and prognosis of preeclampsia (PE). Small RNA sequencing of maternal serum prospectively collected from participants undergoing evaluation for suspected PE revealed distinct patterns of ex-miRNA expression among different categories of hypertensive disorders in pregnancy. Applying an iterative machine learning method...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38117879
DOI: 10.1126/sciadv.adg7545

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