Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early prediction of preeclampsia in pregnancy with cell-free RNA

9 Feb 2022

Abstract excerpt

Abstract Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study the development of pregnancy-related complications in a non-invasive manner and to bridge gaps in clinical care 1–4 . Here we used 404 blood samples from 199 pregnant mothers to identify and validate cfRNA transcriptomic changes that are associated with preeclampsia, a multi-organ syndrome that is the second...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35140405
DOI: 10.1038/s41586-022-04410-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early prediction of preeclampsia in pregnancy with cell-free RNAPMID 35140405Read ↗

Early prediction of preeclampsia in pregnancy with circulating cell-free RNASemantic proximity Read ↗

RNA profiles reveal signatures of future health and disease in pregnancySemantic proximity Read ↗

Molecular subtyping of hypertensive disorders of pregnancySemantic proximity Read ↗

Placenta at single-cell resolution in early and late preeclampsia: insights and clinical implicationsSemantic proximity Read ↗

Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamicsSemantic proximity Read ↗

Improved Prediction Accuracy for Late-Onset Preeclampsia Using cfRNA Profiles: A Comparative Study of Marker Selection StrategiesSemantic proximity Read ↗

Characterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learningSemantic proximity Read ↗

Circulating transcripts in maternal blood reflect a molecular signature of early-onset preeclampsiaSemantic proximity Read ↗

Investigating Pregnancy and Its Complications Using Circulating Cell-Free RNA in Women's Blood During GestationSemantic proximity Read ↗

Maternal whole blood mRNA signatures identify women at risk of early preeclampsia: a longitudinal studySemantic proximity Read ↗

Blood biomarkers representing maternal-fetal interface tissues used to predict early-and late-onset preeclampsia but not COVID-19 infectionSemantic proximity Read ↗

Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.