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Article

A blood-based miRNA signature for early non-invasive diagnosis of preeclampsia

13 Sept 2022

Abstract excerpt

BACKGROUND: Preeclampsia (PE) is a multisystemic maternal syndrome with substantial maternal and fetal morbidity and mortality. Currently, there is no clinically viable non-invasive biomarker assay for early detection, thus limiting the effective prevention and therapeutic strategies for PE. METHODS: We conducted a discovery-training-validation three-phase retrospective and prospective study with cross-platform...

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PMID: 36096786
DOI: 10.1186/s12916-022-02495-x

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