Article
Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Feb 2018
Hainsworth John D, Meric-Bernstam Funda, Swanton Charles, Hurwitz Herbert, Spigel David R, Sweeney Christopher, Burris Howard, Bose Ron, Yoo Bongin, Stein Alisha, Beattie Mary, Kurzrock Razelle
Abstract excerpt
Purpose Detection of specific molecular alterations in tumors guides the selection of effective targeted treatment of patients with several types of cancer. These molecular alterations may occur in other tumor types for which the efficacy of targeted therapy remains unclear. The MyPathway study evaluates the efficacy and safety of selected targeted therapies in tumor types that harbor relevant genetic alterations...
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