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Article

Genetic and observational associations of lung function with gastrointestinal tract diseases: pleiotropic and mendelian randomization analysis.

Respiratory research - 15 Dec 2023

Jiang Minghui, Hao Xingjie, Jiang Yi, Li Si, Wang Chaolong, Cheng Shanshan

Abstract excerpt

BACKGROUND: The two-way communications along the gut-lung axis influence the immune function in both gut and lung. However, the shared genetic characteristics of lung function with gastrointestinal tract (GIT) diseases remain to be investigated. METHODS: We first investigated the genetic correlations between three lung function traits and four GIT diseases. Second, we illustrated the genetic overlap by...

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Identifiers

PMID: 38102678
DOI: 10.1186/s12931-023-02621-0
PMCID: PMC10724909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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