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Article

WNT‐activated, MYC ‐amplified medulloblastoma displaying intratumoural heterogeneity

14 Dec 2023

Abstract excerpt

Medulloblastomas (MB) are the most commonly occurring malignant brain tumour in childhood. The mainstay of therapy incorporates gross total resection followed by craniospinal irradiation (CSI) and chemotherapy. To guide post-surgical treatment, patients are assigned to average-risk or high-risk groups depending on their age at presentation, the presence of metastases at diagnosis and the extent of postoperative...

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PMID: 38093348
DOI: 10.1111/nan.12945

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