Article
γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
27 Nov 2023
Abstract excerpt
Cervical cancer is a leading cause of death among women globally, primarily driven by high-risk papillomaviruses. However, the effectiveness of chemotherapy is limited, underscoring the potential of personalized immunotherapies. Patient-derived organoids, which possess cellular heterogeneity, proper epithelial architecture and functionality, and long-term propagation capabilities offer a promising platform for...
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