Article

Developing <i>in vitro</i> patient derived CERvical Cancer OrganoidS (CERCOS) as a potential preclinical tool in cervical cancer research

2025-06-25

Abstract excerpt

Advanced cervical cancer remains a major cause of mortality in women worldwide as it has limited treatment options and recurrence is very common. This highlights the necessity to develop patient derived organoids (PDOs) as preclinical models, that can recapitulate the clinical heterogeneity of the cancer in terms of molecular features, and genetic background. The PDOs have potential for guiding personalized treatm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 636b22ab-e61e-50a6-93c1-9e0f20e99db2
DOI: 10.1101/2025.06.19.660648

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Developing <i>in vitro</i> patient derived CERvical Cancer OrganoidS (CERCOS) as a potential preclinical tool in cervical cancer researchDOI 10.1101/2025.06.19.660648Read

A Promising New Model: Establishment of Patient‐Derived Organoid Models Covering HPV‐Related Cervical Pre‐Cancerous Lesions and Their CancersSemantic proximity Read

Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinomaSemantic proximity Read

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancerSemantic proximity Read

Patient-derived organoids as personalized avatars and a potential immunotherapy model in cervical cancerSemantic proximity Read

PATIENT-DERIVED ORGANOIDS CAPTURE HISTOLOGICAL, MOLECULAR AND THERAPEUTIC HETEROGENEITY IN PHARYNGEAL AND LARYNGEAL SQUAMOUS CELL CARCINOMASSemantic proximity Read

Patient-derived organoids assist personalized treatment for a patient with multiple metastatic neuroendocrine carcinoma of the cervixSemantic proximity Read

Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosisSemantic proximity Read

Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristicsSemantic proximity Read

γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoidsSemantic proximity Read

Head and neck cancer patient-derived tumouroid cultures: opportunities and challengesSemantic proximity Read

γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoidsSemantic proximity Read

Establishment and Preclinical Application of Conditional Reprogramming Culture System for Laryngeal and Hypopharyngeal CarcinomaSemantic proximity Read