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Article

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa.

Retrovirology - 5 May 2021

Farinre Omotayo, Gounder Kamini, Reddy Tarylee, Tongo Marcel, Hare Jonathan, Chaplin Beth, Gilmour Jill, Kanki Phyllis, Mann Jaclyn K, Ndung'u Thumbi

Abstract excerpt

BACKGROUND: The HIV-1 epidemic in sub-Saharan Africa is heterogeneous with diverse unevenly distributed subtypes and regional differences in prevalence. Subtype-specific differences in disease progression rate and transmission efficiency have been reported, but the underlying biological mechanisms have not been fully characterized. Here, we tested the hypothesis that the subtypes prevalent in the East Africa,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33952315
DOI: 10.1186/s12977-021-00554-4
PMCID: PMC8097975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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