Article
Mitochondrial DNA mutations in HIV-exposed uninfected infants following the cessation of triple antiretroviral drugs.
The Journal of antimicrobial chemotherapy - 1 Feb 2024
Lian Yuting, Wang Ailing, Wei Lai, Yao Jun, Bulloch Gabriella, Wu Zunyou, Zhao Yan
Abstract excerpt
OBJECTIVES: Mitochondrial mutations in HIV-exposed uninfected (HEU) infants after cessation of ART are rarely studied. We analysed a group of HEU newborns born to mothers with late HIV diagnosis who received three doses of ART immediately after birth. We observed mitochondrial DNA (mtDNA) mutations at different times of withdrawal. METHODS: The study was based on a clinical trial conducted from 2015 to 2020....
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