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Comprehensive Analyses of PANoptosome with Potential Implications in Cancer Prognosis and Immunotherapy

4 Mar 2024

Abstract excerpt

Cell death resistance significantly contributes to poor therapeutic outcomes in various cancers. PANoptosis, a unique inflammatory programmed cell death (PCD) pathway activated by specific triggers and regulated by the PANoptosome, possesses key features of apoptosis, pyroptosis, and necroptosis, but these cannot be accounted for by any of the three PCD pathways alone. While existing studies on PANoptosis have...

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PMID: 38436818
DOI: 10.1007/s10528-024-10687-8

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