Article
A phase II study of atezolizumab with bevacizumab, carboplatin, and paclitaxel for patients with EGFR-mutated NSCLC after TKI treatment failure (NEJ043 study).
European journal of cancer (Oxford, England : 1990) - 1 Jan 2024
Watanabe Satoshi, Furuya Naoki, Nakamura Atsushi, Shiihara Jun, Nakachi Ichiro, Tanaka Hisashi, Nakao Mika, Minato Koichi, Seike Masahiro, Sasaki Shinichi, Kisohara Akira, Takeuchi Susumu, Honda Ryoichi, Takamura Kei, Kagamu Hiroshi, Yoshimura Kenichi, Kobayashi Kunihiko, Kikuchi Toshiaki
Abstract excerpt
INTRODUCTION: Treatment options for patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) after EGFR-tyrosine kinase inhibitor (TKI) treatment failure are limited. An exploratory analysis of 26 patients in the IMpower150 study indicated that treatment with atezolizumab, bevacizumab, carboplatin, and paclitaxel (ABCP) was effective in patients with EGFR-mutated NSCLC....
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