Safety and Patient-Reported outcomes of atezolizumab plus chemotherapy with or without bevacizumab in stage IIIB/IV non-squamous non-small cell lung cancer with EGFR mutation, ALK rearrangement or ROS1 fusion progressing after targeted therapies (GFPC 06-2018 study).

doi:10.1016/j.lungcan.2024.107843

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Article

Safety and Patient-Reported outcomes of atezolizumab plus chemotherapy with or without bevacizumab in stage IIIB/IV non-squamous non-small cell lung cancer with EGFR mutation, ALK rearrangement or ROS1 fusion progressing after targeted therapies (GFPC 06-2018 study).

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2024

Amari Lyria, Tomasini Pascale, Dantony Emmanuelle, Rousseau-Bussac Gaelle, Ricordel Charles, Bigay-Game Laurence, Arpin Dominique, Morel Hugues, Veillon Remi, Justeau Grégoire, Huchot Eric, Fournel Pierre, Vergnenegre Alain, Bizeux Acya, Subtil Fabien, Clarisse Bénédicte, Decroisette Chantal, Chouaid Christos, Greillier Laurent, Bylicki Olivier

Abstract excerpt

BACKGROUND: In an open-label multicenter non-randomized non-comparative phase II study in patients with stage IIIB/IV non-squamous non-small cell lung cancer (NSCLC), oncogenic addiction (EGFR mutation or ALK/ROS1 fusion), with disease progression after tyrosine-kinase inhibitor and no prior chemotherapy (NCT04042558), atezolizumab, carboplatin, pemetrexed with or without bevacizumab showed some promising result....

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PMID: 38830303
DOI: 10.1016/j.lungcan.2024.107843

Genes

ALK
EGFR
ROS1

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