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Combination atezolizumab, bevacizumab, pemetrexed and carboplatin for metastatic EGFR mutated NSCLC after TKI failure.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2021

Lam T C, Tsang K C, Choi H C, Lee V H, Lam K O, Chiang C L, So T H, Chan W W, Nyaw S F, Lim F, Lau J O, Chik J, Kong F M, Lee A W

Abstract excerpt

INTRODUCTION: Acquired resistance to TKI is an important unmet need in the management of EGFR mutated lung cancer. Recent clinical trial IMPower150 suggested that combination approach with VEGF inhibitor, check point inhibitor immunotherapy and platinum-based chemotherapy was effective in oncogene driven lung cancer. The current trial examined the efficacy of a modified regimen in an EGFR mutated cohort. METHODS:...

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PMID: 34303276
DOI: 10.1016/j.lungcan.2021.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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