Article
Near Complete Response to Platinum-based Systemic Chemotherapy in High-risk Upper Tract Urothelial Carcinoma With an ERBB2 Gene Mutation: A Case Report.
Urology - 1 Feb 2024
Weiss Kristin, Abimbola Obafunbi, Miller Kelsey, Kim William Y, Rose Tracy L, Bjurlin Marc A, Gessner Kathryn H
Abstract excerpt
In bladder urothelial carcinoma, ERBB2 mutations have been associated with favorable response to platinum-based neoadjuvant chemotherapy. However, this association has not been reported in upper tract urothelial carcinoma (UTUC). We describe an excellent response to cisplatin-based chemotherapy in metastatic UTUC with an ERBB2 mutation. Our patient is a 54-year-old female with metastatic UTUC who received...
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