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Identification of four neutralizing antigenic sites on the enterovirus D68 capsid

4 Dec 2023

Abstract excerpt

ABSTRACT Enterovirus D68 (EV-D68) is an emerging human pathogen associated with respiratory diseases and/or acute flaccid myelitis. Neutralizing antigenic sites of EV-D68 have not yet been comprehensively studied. In this study, we generated multiple neutralizing monoclonal antibodies (MAbs) directed against EV-D68 prototype or clinical strains. All these antibodies can inhibit EV-D68 attachment. The antibody...

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PMID: 38047678
DOI: 10.1128/jvi.01600-23

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