Urinary markers of the alternative and lectin complement pathway are increased in IgA vasculitis nephritis

Abstract excerpt

ABSTRACT Background IgA vasculitis (IgAV) is the most common form of childhood vasculitis. Nephritis (IgAVN) occurs in 50% of patients and 1–2% progress to chronic kidney disease stage 5. The pathophysiology of nephritis remains largely unknown, but recent evidence suggests that the complement system may be involved. The aim of this cross-sectional study was to explore whether there is evidence of alternative...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Complement system in diseases
• Share to Renal Diseases and Glomerulopathies
• Share to Vasculitis and related conditions