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Article

Complement-Mediated Glomerular Diseases: A Tale of 3 Pathways

3 Jul 2016

Abstract excerpt

A renewed interest in the role of complement in the pathogenesis of glomerular diseases has improved our understanding of their basic, underlying physiology. All 3 complement pathways-classical, lectin, and alternative-have been implicated in glomerular lesions both rare (e.g., dense deposit disease) and common (e.g., IgA nephropathy). Here we review the basic function of these pathways and highlight, with a...

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Share to Complement system in diseases
Share to Renal Diseases and Glomerulopathies
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PMID: 29142924
DOI: 10.1016/j.ekir.2016.06.005

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