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Lysosome-Related Diagnostic Biomarkers for Pediatric Sepsis Integrated by Machine Learning

1 Nov 2023

Abstract excerpt

Background: There is currently no biomarker that can reliably identify sepsis, despite recent scientific advancements. We systematically evaluated the value of lysosomal genes for the diagnosis of pediatric sepsis. Methods: Three datasets (GSE13904, GSE26378, and GSE26440) were obtained from the gene expression omnibus (GEO) database. LASSO regression analysis and random forest analysis were employed for...

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PMID: 38034045
DOI: 10.2147/jir.s437110

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