Anticancer effects of alpelisib on PIK3CA-mutated canine mammary tumor cell lines

Abstract excerpt

Canine mammary tumors (CMTs) are commonly observed in old and unspayed female dogs. Recently, dogs have been increasingly spaying at a young age to prevent mammary tumors. These CMTs require extensive local excision and exhibit a high probability of metastasis to the regional lymph nodes and lungs during malignancy. However, the molecular and biological mechanisms underlying CMT development have not been fully...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Infectious Diseases and Mycology
• Share to PI3K/AKT/mTOR signaling in cancer
• Share to Veterinary Oncology Research