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Article

Insights on the mechanism of flecainide in catecholaminergic polymorphic ventricular tachycardia.

Journal of medicine and life - 1 Aug 2023

Davidson Ross, Medeiros Maria

Abstract excerpt

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by defective cardiac ryanodine receptor (RyR2) calcium release during times of adrenergic stimulation, resulting in bidirectional or polymorphic ventricular tachycardia. Flecainide is a class 1c anti-arrhythmic drug that has demonstrated therapeutic efficacy in treating CPVT. However, its mechanism of...

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Source

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Identifiers

PMID: 38024821
DOI: 10.25122/jml-2023-0191
PMCID: PMC10652680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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