Article
Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Jun 2011
Pott Christian, Dechering Dirk G, Reinke Florian, Muszynski Adam, Zellerhoff Stephan, Bittner Alex, Köbe Julia, Wasmer Kristina, Schulze-Bahr Eric, Mönnig Gerold, Kotthoff Stefan, Eckardt Lars
Abstract excerpt
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmogenic disease that can cause sudden cardiac death due to ventricular fibrillation (VF). While pharmacological therapy with beta-blockers and/or Ca(2)(+) antagonists is often unreliable, a recent study has demonstrated that flecainide can effectively suppress arrhythmia in a murine model of CPVT as well as clinically in two human...
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