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Identification of potential diagnostic biomarkers for tenosynovial giant cell tumour by integrating microarray and single-cell RNA sequencing data

28 Nov 2023

Abstract excerpt

PURPOSE: Tenosynovial giant cell tumour (TGCT) is a benign hyperplastic and inflammatory disease of the joint synovium or tendon sheaths, which may be misdiagnosed due to its atypical symptoms and imaging features. We aimed to identify biomarkers with high sensitivity and specificity to aid in diagnosing TGCT. METHODS: Two scRNA-seq datasets (GSE210750 and GSE152805) and two microarray datasets (GSE3698 and...

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Share to Bone Tumor Diagnosis and Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38017559
DOI: 10.1186/s13018-023-04279-2

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