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Identification of diagnostic mRNA biomarkers in whole blood for ankylosing spondylitis using WGCNA and machine learning feature selection

12 Sept 2022

Abstract excerpt

Ankylosing spondylitis (AS) is a common inflammatory spondyloarthritis affecting the spine and sacroiliac joint that finally results in sclerosis of the axial skeleton. Aside from human leukocyte antigen B27, transcriptomic biomarkers in blood for AS diagnosis still remain unknown. Hence, this study aimed to investigate credible AS-specific mRNA biomarkers from the whole blood of AS patients by analyzing an mRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36172367
DOI: 10.3389/fimmu.2022.956027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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