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Kristen rat sarcoma virus (KRAS) G12F-positive non-small cell lung cancer mimicking KRAS G12C positivity: A case report.

Thoracic cancer - 1 Jan 2024

Oi Issei, Ito Takanori, Saito Zentaro, Imakita Takuma, Kanai Osamu, Fujita Kohei, Tachibana Hiromasa, Mio Tadashi

Abstract excerpt

Searching for driver gene alteration is a prerequisite for chemotherapy of non-small cell lung cancer. Due to its high sensitivity and concordance rate, the Amoy Dx Pan Lung Cancer PCR panel has been approved and is widely used in Japan. In this report, we describe a case in which a positive result for Kristen rat sarcoma virus (KRAS) exon2 p.G12F, a rare KRAS mutation, may have led to a false-positive result for...

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Identifiers

PMID: 38010032
DOI: 10.1111/1759-7714.15171
PMCID: PMC10803219

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