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Article

Elderly male smokers with right lung tumors are viable candidates for KRAS mutation screening.

Scientific reports - 7 Jan 2016

Yang Yang, Shi Chun, Sun Hui, Yin Wei, Zhou Xiao, Zhang Lei, Jiang Gening

Abstract excerpt

Genetic aberrations in tumor driver genes provide specific molecular targets for therapeutic intervention, which can greatly improve therapeutic outcomes. Here, we analyzed the mutational frequency of EGFR and KRAS gene, as well as EML4-ALK rearrangement, and summarized the clinicopathological characters of Chinese lung cancer patients. We detected the mutation spectrum of 1033 primary lung cancer patients. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26739511
DOI: 10.1038/srep18566
PMCID: PMC4703983

Genes

KRAS
EGFR
ALK
EML4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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